The CD158f antibody (PE) from MyBioSource.com is a Mouse Monoclonal antibody. The CD158f antibody (PE) has been validated for the following applications: Flow Cytometry.
Description
Mouse monoclonal CD158f antibody (PE)
This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain. The UP-R1 antibody has been shown to inhibit NK cytotoxicity